Neil Patrick Harris the next David Letterman?

Neil Patrick Harris filled in for Regis Philbin last week on Live with Regis & Kelly and proved that he has what it takes to be a successful talk show host. Harris was among a string of male hosts to fill the seat, while Regis is recovering from heart surgery.

Harris was funny, relaxed, and had great chemistry with Kelly Ripa. He even jovially rolled with the punches, when a guest caller screamed, “Doogie!” in reference to his beloved classic TV character Doogie Howser, M.D. Harris is a master impressionist and does a hilarious Regis. So, if Harris’ acting career ever goes South, perhaps he should look into a career of late-night chatting.

He already has Dave Letterman’s shtick down pat, including voice inflections, mannerisms, and biting comedy. His Letterman impression is the best I’ve ever seen. In this clip from Harris’ show How I Met Your Mother, his character Barney comes up with a list of nicknames for the moving truck that he parked outside the bar and was using as a love nest to entertain the ladies.

Letterman, if you ever need another guest host, I think we’ve found your guy. Here’s Barney’s Top 10 List. Hit play and prepare to laugh.

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